Mapping of the proteinase b structural gene PRB1, in Saccharomyces cerevisiae and identification of nonsense alleles within the locus

Genetics. 1980 Sep;96(1):137-46. doi: 10.1093/genetics/96.1.137.

Abstract

We report the mapping of the structural gene for proteinase B, PRB1. It is located 1.1 cM proximal to CAN1 on the left arm of chromosome V of Saccharomyces cerevisiae. We have identified 34 amber and 12 ochre mutations among the 126 prb1 mutations in our collection.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Chromosome Mapping*
  • DNA Replication
  • Endopeptidases / genetics*
  • Genes*
  • Genetic Linkage
  • Mutation
  • Phenotype
  • Recombination, Genetic
  • Saccharomyces cerevisiae / genetics*

Substances

  • Endopeptidases