Aromatic-dependent Salmonella Typhimurium Are Non-Virulent and Effective as Live Vaccines

Nature. 1981 May 21;291(5812):238-9. doi: 10.1038/291238a0.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Bacterial Vaccines*
  • Drug Resistance, Microbial
  • Mice
  • Mice, Inbred C57BL
  • Mutation
  • Phenylalanine
  • Salmonella typhimurium / genetics
  • Salmonella typhimurium / pathogenicity*
  • Species Specificity
  • Tetracycline / pharmacology
  • Transduction, Genetic
  • Tryptophan / metabolism
  • Tyrosine / metabolism

Substances

  • Bacterial Vaccines
  • Tyrosine
  • Phenylalanine
  • Tryptophan
  • Tetracycline