The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues

Immunology. 1981 Apr;42(4):593-600.

Abstract

The localisation of subpopulations of T lymphocytes as defined by the monoclonal antibodies W3/25 and MRC OX 8 was determined by an indirect immunoperoxidase technique on cryostat sections of rat lymphoid tissues. Both subpopulations were present throughout T-dependent areas with only scattered T cells, largely W3/25 positive, in the B areas. The W3/25 antigen was also found on macrophages in the medulla of lymph nodes and in the peritoneal cavity and liver.

MeSH terms

  • Animals
  • Antibodies
  • Ascitic Fluid / cytology
  • Ascitic Fluid / immunology
  • Immunoenzyme Techniques
  • Lymph Nodes / immunology
  • Lymphoid Tissue / immunology*
  • Rats
  • Spleen / immunology
  • T-Lymphocytes / classification
  • T-Lymphocytes / immunology*

Substances

  • Antibodies