Abstract
The nucleotide sequences of the recombinant DNA inserts of three bacterial plasmid clones containing nearly all of the rat serum albumin mRNA have been determined. A statistical analysis of the nucleotide sequence reveals a pattern of repeated internal homology that confirms the "intragenic triplication" model of albumin evolution.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Amino Acid Sequence
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Animals
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Base Sequence
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Cloning, Molecular
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DNA, Recombinant
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Escherichia coli / genetics
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Plasmids
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RNA, Messenger* / genetics
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Rats / genetics*
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Repetitive Sequences, Nucleic Acid
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Serum Albumin / genetics*
Substances
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DNA, Recombinant
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RNA, Messenger
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Serum Albumin