Conductivity of drugs used for iontophoresis

J Pharm Sci. 1978 Oct;67(10):1439-43. doi: 10.1002/jps.2600671031.

Abstract

The electrical conductivities of drugs were measured in vitro using a conductivity MHO-meter. These experiments indicate that local anesthetics, vasoconstrictors, some corticosteroids, several anticancer drugs, and several antiviral agents are suitable for iontophoresis. The contribution to conductivity of buffers and nonspecific ions in the same solution with the drug also was defined.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adrenal Cortex Hormones / administration & dosage
  • Anesthetics, Local / administration & dosage
  • Antineoplastic Agents / administration & dosage
  • Antiviral Agents / administration & dosage
  • Electric Conductivity
  • Iontophoresis*
  • Pharmaceutical Preparations / administration & dosage*
  • Vasoconstrictor Agents / administration & dosage

Substances

  • Adrenal Cortex Hormones
  • Anesthetics, Local
  • Antineoplastic Agents
  • Antiviral Agents
  • Pharmaceutical Preparations
  • Vasoconstrictor Agents