A method for quantitating color measurements in dextrose solutions by using a color difference meter is described. This method was shown to correlate well with standard American Public Health Association (APHA) color measurements. A mathematical relationship was developed relating yellowness index values to APHA numbers as described in the USP for dextrose solutions. This relationship was tested by comparing the results from standard APHA color tests on laboratory samples of autoclaved dextrose solutions to APHA numbers calculated from yellowness index values for the same samples.