Insidious onset of acute alveolar hypoventilation following intermittent positive-pressure breathing (IPPB)

Respiration. 1981;41(3):199-201. doi: 10.1159/000194379.


2 patients developing acute alveolar hypoventilation following IPPB therapy are presented. The hypoventilation occurred insidiously following therapy. It is hypothesized that respiratory center depression from excessive oxygen administration caused the hypoventilation. When the IPPB machines were driven by compressed air instead of oxygen, this complication was revealed in 1 of the patients.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Aged
  • Dyspnea / therapy
  • Humans
  • Hypoventilation / etiology*
  • Intermittent Positive-Pressure Breathing / adverse effects*
  • Male
  • Positive-Pressure Respiration / adverse effects*
  • Pulmonary Alveoli / physiopathology*