A program package for quantitative analysis of histologic structure and remodeling dynamics of bone

Comput Programs Biomed. Sep-Dec 1981;13(3-4):191-201. doi: 10.1016/0010-468x(81)90098-2.


Quantitative bone histology has become an increasingly valuable tool for the management and diagnosis of metabolic bone disease. A new computer-assisted method for quantitative analysis of bone histology which combines the advantages of discriminatory input by the investigator with a significant reduction of evaluation time is presented. These programs allow the analysis of a sufficient number of subjects from different populations for the establishment of normative data, and are useful in the diagnosis and documentation of the treatment of metabolic bone disease.

MeSH terms

  • Bone Diseases, Metabolic / diagnosis*
  • Bone and Bones / anatomy & histology
  • Bone and Bones / pathology*
  • Computers*
  • Diagnosis, Computer-Assisted
  • Histological Techniques
  • Humans
  • Osteocytes / cytology