Abstract
In rats injected with an arthropathogenic dose of streptococcal cell wall fragments, serum hemolytic activity decreased over the first 24 h and was then elevated from days 2 through 6 after injection. Hemolytic activity was again elevated at days 16 and 40. Levels of activity of alternative complement pathway, C3, and factor D were also altered.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Complement Activation*
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Complement C3 / analysis
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Complement Factor D / metabolism
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Complement Pathway, Alternative*
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Female
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Peptidoglycan / pharmacology*
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Polysaccharides, Bacterial / pharmacology*
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Rats
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Streptococcus pyogenes / analysis*
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Time Factors
Substances
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Complement C3
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Peptidoglycan
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Polysaccharides, Bacterial
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Complement Factor D