Nuclear magnetic resonance (NMR) in vivo studies: known thresholds for health effects

J Comput Assist Tomogr. 1981 Dec;5(6):800-11. doi: 10.1097/00004728-198112000-00003.

Abstract

Three sources of harmful health effects from nuclear magnetic resonance (NMR) in vivo techniques have been examined with the following conclusions: (a) Static magnetic fields. Harmful effects on humans and reproducible cellular, biochemical, or genetic effects have not yet been observed at fields less than 2 Tesla (20,000 gauss). (b) Changing magnetic fields. The threshold for effects of induced currents is above that produced from less than 1 to 100 Hz sinusoidal field changes with a maximum field of 5 mT (50 gauss). Waveform, repetition rate maximum B field, and duration of exposure are parameter requiring further study. (c) Radiofrequency (RF) heating. A practical upper level for absorbed power is 4 W/kg in medically important studies of short duration (less than 10 min). For long-term studies, 1.5 W/kg is a reasonable level in low humidity environments. The power absorbed by the subject can be estimated by measuring the RF coil Q before and after the subject is placed in the NMR instrument. Large metal objects will absorb power in proportion to the conductivity of the device or prosthesis.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Blood-Brain Barrier
  • Cell Physiological Phenomena
  • Electrocardiography
  • Enzymes / metabolism
  • Humans
  • Kinetics
  • Magnetic Resonance Spectroscopy
  • Magnetics / adverse effects*
  • Neural Conduction
  • Risk

Substances

  • Enzymes