Marked hyperinsulinemia after glucose challenge in patients with diffuse idiopathic skeletal hyperostosis

J Rheumatol. Nov-Dec 1981;8(6):965-8.

Abstract

The insulin response after a glucose challenge was studied in 11 male patients with diffuse idiopathic skeletal hyperostosis (DISH) and in 8 age, sex and weight matched controls. There was significant hyperinsulinemia in the DISH group, most marked at 2 h after the glucose challenge. Growth hormone levels were found to be normal in each group. The marked hyperinsulinemia in patients with DISH may play a role in the pathogenesis of this condition.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Bone Diseases / blood*
  • Glucose Tolerance Test*
  • Humans
  • Insulin / blood*
  • Male
  • Middle Aged

Substances

  • Insulin