The 20 gauge Turner biopsy needle was used to obtain both cytologic and histologic specimens during aspiration biopsy. In 42 patients with proven malignancy, a positive reading was obtained in 83% by histology alone and in 90% by histology and cytology combined. Histology yielded positive diagnoses in most patients with false-negative cytology. Histology also provided cell type or tissue origin in most cases. This technique increases the value of aspiration biopsy and also makes it a viable diagnostic tool where cytology services are not available.