Cardiac performance in response to PEEP in patients with cardiac dysfunction

Crit Care Med. 1982 Jun;10(6):358-60. doi: 10.1097/00003246-198206000-00002.


The effect of PEEP on cardiac performance was evaluated in 21 patients with left ventricular (LV) dysfunction. Twenty-three data sets were divided into three groups according to pulmonary arterial wedge pressure (PAWP). In three of four group A data sets (PAWP = 12 mm Hg), cardiac output (CO) decreased when PEEP was added. In four of six group B data sets (PAWP = 14-18 mm Hg) and in 12 of 13 group C data sets (PAWP less than or equal to 19 mm Hg), CO increased with addition of PEEP. In group C, the mean increase in CO was 500 ml/min, and the mean level of best PEEP was 3.9 cm H2O. When PAWP exceeded 18 mm Hg, PEEP was safe and in many instances augmented CO.

MeSH terms

  • Cardiac Output
  • Heart / physiology*
  • Heart Diseases / physiopathology*
  • Heart Failure / complications
  • Heart Failure / physiopathology
  • Humans
  • Myocardial Infarction / complications
  • Myocardial Infarction / physiopathology
  • Oxygen / blood
  • Positive-Pressure Respiration*
  • Pulmonary Wedge Pressure
  • Shock, Cardiogenic / complications
  • Shock, Cardiogenic / physiopathology
  • Veins


  • Oxygen