Abstract
Sixty-two patients with osteoarthrosis entered a 10-week double-blind cross-over trial of diflunisal and naproxen. Eight patients withdrew for drug-related reason, and seven for other reasons. There was no statistically significant difference in parameters of disease activity on each treatment period, but naproxen produced fewer withdrawals due to drug-related side-effects.
Publication types
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Clinical Trial
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Clinical Trials as Topic
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Diflunisal / adverse effects
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Diflunisal / therapeutic use*
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Double-Blind Method
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Female
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Humans
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Male
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Naproxen / adverse effects
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Naproxen / therapeutic use*
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Osteoarthritis / drug therapy*
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Salicylates / therapeutic use*
Substances
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Salicylates
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Naproxen
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Diflunisal