Naproxen and diflunisal in osteoarthrosis

Rheumatol Rehabil. 1982 May;21(2):95-7. doi: 10.1093/rheumatology/21.2.95.

Abstract

Sixty-two patients with osteoarthrosis entered a 10-week double-blind cross-over trial of diflunisal and naproxen. Eight patients withdrew for drug-related reason, and seven for other reasons. There was no statistically significant difference in parameters of disease activity on each treatment period, but naproxen produced fewer withdrawals due to drug-related side-effects.

Publication types

  • Clinical Trial
  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Clinical Trials as Topic
  • Diflunisal / adverse effects
  • Diflunisal / therapeutic use*
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Naproxen / adverse effects
  • Naproxen / therapeutic use*
  • Osteoarthritis / drug therapy*
  • Salicylates / therapeutic use*

Substances

  • Salicylates
  • Naproxen
  • Diflunisal