Experimental studies on the olfactory marker protein. II. Appearance of the olfactory marker protein during differentiation of the olfactory sensory neurons of mouse: an immunohistochemical and autoradiographic study

Brain Res. 1982 May 6;239(1):245-50. doi: 10.1016/0006-8993(82)90846-0.


The time interval between the incorporation of [3H]thymidine and the appearance of olfactory marker protein (OMP) in autoradiographically labeled neurons which have differentiated from stem cells, has been determined by autoradiographic and immunohistochemical techniques. The first [3H]thymidine-labeled, OMP-containing elements have been observed 7 days after administration of the radioactive thymidine. This result allows some speculation on the potential function of the olfactory marker protein.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Autoradiography
  • Cell Differentiation
  • DNA Replication
  • Fluorescent Antibody Technique
  • Kinetics
  • Male
  • Mice
  • Mice, Inbred Strains
  • Nerve Tissue Proteins / analysis*
  • Neurons / physiology*
  • Olfactory Bulb / physiology*
  • Olfactory Marker Protein
  • Tritium


  • Nerve Tissue Proteins
  • Olfactory Marker Protein
  • Omp protein, mouse
  • Tritium