Synthesis of thromboxane B2 metabolites

N A Nelson; R W Jackson; O K Sebek

doi:10.1016/0090-6980(78)90204-6

Synthesis of thromboxane B2 metabolites

Prostaglandins. 1978 Jul;16(1):85-92. doi: 10.1016/0090-6980(78)90204-6.

Authors

N A Nelson, R W Jackson, O K Sebek

PMID: 704927
DOI: 10.1016/0090-6980(78)90204-6

Abstract

This paper reports the synthesis of 11-dehydrothromboxane B2 methyl ester (II), 15-dehydrothromboxane B2 methyl ester (III), 15-dehydro-13, 14-dihydrothromboxane B2 (XII) and 2,3-dinorthromboxane B2 methyl ester (XV). These compounds, as their free acids, have been reported to be thromboxane metabolites.

MeSH terms

Methods
Mycobacterium / metabolism
Thromboxane B2 / chemical synthesis*
Thromboxane B2 / metabolism
Thromboxanes / chemical synthesis*

Substances

Thromboxanes
Thromboxane B2