Enhancement of relaxation rate with paramagnetic contrast agents in NMR imaging

J Comput Tomogr. 1981 Dec;5(6):543-7. doi: 10.1016/0149-936x(81)90089-8.


Enhancement of spin-lattice relaxation using oral ferric chloride and using inhaled oxygen is illustrated. A 0.06% solution of ferric chloride reduced the spin-lattice relaxation time in the fundus of the stomach from 730 ms to 285 ms. Ferric chloride may be useful as a bowel-labeling agent. In 5 volunteers inhalation of 100% oxygen decreased the mean observed spin-lattice relaxation time of blood within the left ventricular cavity. Although the change was small, it may have important uses in monitoring metabolic processes.

MeSH terms

  • Abdomen
  • Adult
  • Chlorides
  • Ferric Compounds / administration & dosage*
  • Heart
  • Humans
  • Image Enhancement / methods
  • Iron / administration & dosage*
  • Magnetic Resonance Spectroscopy / methods*
  • Oxygen / administration & dosage*


  • Chlorides
  • Ferric Compounds
  • Iron
  • Oxygen
  • ferric chloride