Widespread periodic intrinsic connections in the tree shrew visual cortex

Science. 1982 Mar 19;215(4539):1532-4. doi: 10.1126/science.7063863.


Intrinsic connections within the tree shrew (Tupaia glis) visual cortex (area 17) are organized in periodic stripelike patterns within layers I, II, and III. This anatomical network resembles the regularly organized stripes of 2-deoxyglucose accumulation seen after stimulation of alert animals with uniformly oriented lines. Such connections imply that widespread lateral interactions are superimposed on the retinotopic organization of area 17 and suggest alternative interpretations of cortical columns.

Publication types

  • Historical Article
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • History, 19th Century
  • Horseradish Peroxidase
  • Neural Pathways / cytology
  • Tupaiidae
  • Visual Cortex / cytology*


  • Horseradish Peroxidase