Wheat fibre and irritable bowel syndrome. A controlled trial

Lancet. 1977 Aug 27;2(8035):417-8. doi: 10.1016/s0140-6736(77)90605-5.


Twenty-six patients with irritable bowel syndrome entered a controlled trial of diets with a high or low wheat-fibre content. After 6 weeks on the high-wheat fibre regimen there was significant improvement in symptoms and an objective change in colonic motor activity. No such improvement occurred on the low-fibre regimen. Patients with irritable bowel syndrome should be encouraged to increase their daily intake of wheat fibre.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Cellulose / administration & dosage*
  • Cellulose / therapeutic use*
  • Clinical Trials as Topic
  • Colon / physiopathology
  • Colonic Diseases, Functional / diet therapy*
  • Colonic Diseases, Functional / physiopathology
  • Dietary Fiber / therapeutic use*
  • Evaluation Studies as Topic
  • Female
  • Humans
  • Male
  • Middle Aged
  • Peristalsis
  • Triticum*


  • Dietary Fiber
  • Cellulose