ABH secretor status and pulmonary function

Am J Epidemiol. 1982 Mar;115(3):367-70. doi: 10.1093/oxfordjournals.aje.a113314.

Abstract

Among current cigarette smokers in the Northwick Park Heart Study in N.W. London, England, secretors of ABH antigen had a higher mean peak expiratory flow rate than did nonsecretors. The relationship was independent of other factors known to affect peak expiratory flow rate. No significant differences in peak expiratory flow rate by secretor status were detected in nonsmokers or in pipe and cigar smokers, although a smaller difference was seen among secretors and nonsecretors who were ex-cigarette smokers than among those who were current cigarette smokers. It is concluded that secretion of ABH antigen into the respiratory tract may have a protective effect against pulmonary damage by noxious agents.

MeSH terms

  • ABO Blood-Group System*
  • Adolescent
  • Adult
  • Female
  • Humans
  • London
  • Male
  • Middle Aged
  • Peak Expiratory Flow Rate
  • Prospective Studies
  • Regression Analysis
  • Smoking*

Substances

  • ABO Blood-Group System