Metabolism, distribution, and excretion of the flame retardant, tris(2,3-dibromopropyl) phosphate (tris-bp) in the rat: identification of mutagenic and nephrotoxic metabolites

Toxicol Appl Pharmacol. 1982 Mar 30;63(1):105-19. doi: 10.1016/0041-008x(82)90030-8.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Bile / metabolism
  • Biotransformation
  • Flame Retardants / metabolism*
  • Kidney / drug effects*
  • Kinetics
  • Male
  • Mutagens / isolation & purification*
  • Mutagens / metabolism
  • Organophosphates / metabolism*
  • Organophosphates / toxicity
  • Organophosphorus Compounds / metabolism*
  • Polyuria / chemically induced
  • Rats
  • Rats, Inbred Strains
  • Tissue Distribution

Substances

  • Flame Retardants
  • Mutagens
  • Organophosphates
  • Organophosphorus Compounds
  • tris(2,3-dibromopropyl)phosphate