Nonoliguric acute renal failure associated with a low fractional excretion of sodium

Ann Intern Med. 1982 May;96(5):597-600. doi: 10.7326/0003-4819-96-5-597.


Measurement of the fractional excretion of sodium has been recommended as a useful clinical tool in evaluating acute renal failure. Six patients with nonoliguric acute renal failure had a fractional excretion of sodium less than or equal to 1.0%; these patients had severe liver dysfunction, which suggested a sodium-avid state. A review of the literature showed that in patients with other sodium-avid states (congestive heart failure, nephrotic syndrome, and burns) the fractional excretion of sodium was frequently less than or equal to 1.0%. The fractional excretion of sodium is thus a less useful diagnostic test in patients whose clinical state makes them sodium avid.

MeSH terms

  • Acute Kidney Injury / blood
  • Acute Kidney Injury / complications
  • Acute Kidney Injury / urine*
  • Adult
  • Aged
  • Creatinine / blood
  • Creatinine / urine
  • Female
  • Humans
  • Male
  • Middle Aged
  • Oliguria / etiology
  • Sodium / blood
  • Sodium / urine*


  • Sodium
  • Creatinine