Erythrocyte digoxin concentration

Clin Pharmacol Ther. 1982 May;31(5):541-7. doi: 10.1038/clpt.1982.75.


Plasma and erythrocyte digoxin concentrations from patients on digoxin maintenance therapy were measured and the results from patients with toxic and those with nontoxic drug levels were compared. Digoxin cumulation and release in plasma and erythrocyte were also studied. Our results indicate that erythrocyte digoxin concentration may be useful in distinguishing toxic and nontoxic drug levels.

MeSH terms

  • Adult
  • Aged
  • Digoxin / adverse effects
  • Digoxin / blood*
  • Erythrocytes / metabolism*
  • Female
  • Heart Failure / blood
  • Humans
  • Kinetics
  • Male
  • Middle Aged
  • Time Factors


  • Digoxin