Platelet activation by non-coagulant snake venom components

Toxicon. 1982;20(1):279-87. doi: 10.1016/0041-0101(82)90227-6.

Abstract

Platelet activation by non-coagulant components of snake venoms is reviewed, with particular emphasis on the effects of convulxin. The latter is present in the venom of Crotalus durissus cascavella, and induces ADP and thromboxane - independent platelet aggregation. Convulxin and similar proteins are tools for the study of platelet functions.

Publication types

  • Comparative Study

MeSH terms

  • Adenosine Diphosphate / pharmacology
  • Agglutination
  • Animals
  • Blood Platelets / physiology
  • Crotalid Venoms / pharmacology
  • Indomethacin / pharmacology
  • Platelet Aggregation / drug effects*
  • Snake Venoms / pharmacology*
  • Species Specificity
  • Thromboxanes / pharmacology

Substances

  • Crotalid Venoms
  • Snake Venoms
  • Thromboxanes
  • Adenosine Diphosphate
  • Indomethacin