[Inheritance of psoriasis. Analysis of 2035 family histories]

Hautarzt. 1982 Apr;33(4):214-7.
[Article in German]


Detailed pedigrees were established in 2,035 families with psoriasis, including 30 twin pairs, and evaluated by means of computer analysis. The following results on the devolution of psoriasis were drawn: the hypotheses of the irregular dominant and the bifactorial recessive inheritance appear to be inacceptable. The findings suggest a multifactorial etiology of psoriasis with a polygenic mode of inheritance. The risk for relatives to be affected by psoriasis is calculated.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Diseases in Twins
  • Female
  • Germany, West
  • Humans
  • Male
  • Psoriasis / epidemiology
  • Psoriasis / genetics*