[Inheritance of psoriasis. Analysis of 2035 family histories]

Hautarzt. 1982 Apr;33(4):214-7.
[Article in German]

Abstract

Detailed pedigrees were established in 2,035 families with psoriasis, including 30 twin pairs, and evaluated by means of computer analysis. The following results on the devolution of psoriasis were drawn: the hypotheses of the irregular dominant and the bifactorial recessive inheritance appear to be inacceptable. The findings suggest a multifactorial etiology of psoriasis with a polygenic mode of inheritance. The risk for relatives to be affected by psoriasis is calculated.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Diseases in Twins
  • Female
  • Germany, West
  • Humans
  • Male
  • Psoriasis / epidemiology
  • Psoriasis / genetics*