Autosomal dominantly inherited adductor laryngeal paralysis--a new syndrome with a suggestion of linkage to HLA

Clin Genet. 1978 Nov;14(5):265-70. doi: 10.1111/j.1399-0004.1978.tb02145.x.

Abstract

A family is reported with autosomal dominantly inherited congenital bilateral adductor paralysis of the larynx. This disorder has apparently not been described previously. A search for linkage in this family with the loci for 19 other genetic markers showed a suggestion of linkage with HLA and GLO, and accordingly a suggestion that the locus for this disorder may be assigned to chromosome 6.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Aged
  • Child
  • Child, Preschool
  • Chromosomes, Human, 6-12 and X
  • Female
  • Genes, Dominant
  • Genetic Linkage*
  • Glyoxylates
  • HLA Antigens*
  • Humans
  • Male
  • Pedigree
  • Syndrome
  • Vocal Cord Paralysis / genetics*

Substances

  • Glyoxylates
  • HLA Antigens