Suspected acute cholecystitis. Comparison of hepatobiliary scintigraphy versus ultrasonography

Clin Nucl Med. 1982 Aug;7(8):364-7. doi: 10.1097/00003072-198208000-00004.


One hundred ninety-five patients with suspected acute cholecystitis (AC) underwent both hepatobiliary scintigraphy (HBS) and static gray-scale ultrasonography (US) to assess the relative value of each imaging modality in this clinical setting. HBS was performed after the intravenous injection of 5 mCi Tc-99m iprofenin. Abnormal HBS indicative of AC visualized the common bile duct, but not the gallbladder, within 1 to 4 hours after tracer administration. Abnormal US indicative of AC demonstrated cholelithiasis and/or gallbladder wall edema. In this series, HBS surpassed US in sensitivity (98.3% versus 81.4%), specificity (90.2% versus 60.2%), predictive value of an abnormal test (91.4% versus 51.6%), and predictive value of a normal test (100% versus 92%), HBS should be the procedure of choice for the rapid detection of AC.

Publication types

  • Comparative Study

MeSH terms

  • Acute Disease
  • Biliary Tract / diagnostic imaging*
  • Cholecystitis / diagnosis*
  • Cholecystitis / diagnostic imaging
  • Humans
  • Imino Acids
  • Liver / diagnostic imaging*
  • Organotechnetium Compounds*
  • Prospective Studies
  • Radionuclide Imaging
  • Technetium
  • Time Factors
  • Ultrasonography*


  • Imino Acids
  • Organotechnetium Compounds
  • Technetium
  • technetium Tc 99m PIPIDA