Iron and copper in plasma membranes

J Bioenerg Biomembr. 1982 Aug;14(4):241-7. doi: 10.1007/BF00751018.

Abstract

Nonheme iron has been found in pig erythrocyte and mouse liver plasma membranes. The amount found, 8.2 nmol/mg protein in erythrocyte membranes and 7.4 nmol/mg protein in liver plasma membrane, is slightly lower than values reported for endoplasmic reticulum and Golgi apparatus. Less than one-third of the erythrocyte membrane iron can be released by acid treatment, which indicates that most of it is not in the typical iron-sulfur structure. Copper has been found in pig erythrocyte plasma membrane at a concentration of 0.45 nmol/mg protein. These metals may be associated with the redox enzymes of plasma membranes.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Cell Membrane / analysis*
  • Cell Membrane / metabolism
  • Copper / analysis*
  • Copper / blood
  • Electron Transport
  • Erythrocyte Membrane / analysis*
  • Erythrocyte Membrane / metabolism
  • Erythrocytes / analysis*
  • Iron / analysis*
  • Iron / blood
  • Mice
  • Oxidation-Reduction
  • Oxidoreductases / metabolism
  • Swine

Substances

  • Copper
  • Iron
  • Oxidoreductases