Regulation of glucose metabolism in the lung: hexokinase-catalyzed phosphorylation, a rate-limiting step

Life Sci. 1982 Aug 23;31(8):791-4. doi: 10.1016/0024-3205(82)90706-8.


A measurement of uptake and phosphorylation of 2-deoxyglucose in rat lung slices under appropriately designed conditions showed that glucose metabolism in lung at the physiological concentration of the sugar will be limited by the rate of its phosphorylation and not by its transport into the cells.

MeSH terms

  • Animals
  • Biological Transport
  • Glucose / metabolism*
  • Hexokinase / metabolism*
  • In Vitro Techniques
  • Lung / metabolism*
  • Male
  • Phosphorylation
  • Rats
  • Rats, Inbred Strains


  • Hexokinase
  • Glucose