Midfacial necrotizing diseases

Ann Otol Rhinol Laryngol. 1982 Sep-Oct;91(5 Pt 1):541-2. doi: 10.1177/000348948209100515.


Wegener's granulomatosis, a systemic disorder, manifests specific clinical and histopathologic findings that allow it to be separated from an unrelated group of upper airway lesions. Two of these, non-Hodgkin's lymphoma and polymorphic reticulosis, are related and may in fact be variable expressions of a lymphoma. A fourth, and fortunately rare, disorder presents as a severely destructive localized lesion without any specific histopathologic findings.

MeSH terms

  • Diagnosis, Differential
  • Granuloma, Lethal Midline / pathology
  • Granulomatosis with Polyangiitis / pathology*
  • Humans
  • Lymphoma / pathology
  • Necrosis