Argyrophilic cell hyperplasia and an atypical carcinoid tumor in chronic ulcerative colitis

Cancer. 1982 Dec 15;50(12):2920-5. doi: 10.1002/1097-0142(19821215)50:12<2920::aid-cncr2820501235>;2-n.


An unusual case of chronic ulcerative colitis, is presented in which an atypical carcinoid tumor was seen. Many areas of the mucosa showed glandular changes of chronic injury and dysplasia, and in these areas, argyrophilic cell hyperplasia was identified. Data is presented describing the evolution of argyrophilic cell hyperplasia as a reaction to injury, the evolution of carcinoid tumors in argyrophilic cell hyperplasia, and the relationship of the proliferating argyrophilic cells to the proliferating glandular cells in ulcerative colitis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Carcinoid Tumor / complications
  • Carcinoid Tumor / pathology*
  • Colitis, Ulcerative / complications
  • Colitis, Ulcerative / pathology*
  • Colonic Neoplasms / complications
  • Colonic Neoplasms / pathology*
  • Female
  • Humans
  • Intestinal Mucosa / pathology