A clinical study of slow-releasing artificial tears

Ophthalmology. 1978 Aug;85(8):794-800. doi: 10.1016/s0161-6420(78)35610-4.

Abstract

The slow-releasing artificial tear (SR-AT) is a soluble polymer in solid form. Placed in the inferior cul-de-sac and allowed to dissolve, it is used to treat dry-eye patients. The SR-AT was studied in two phases. The short-term cross-over study of 40 patients was completed in October 1976. The long-term open study is still in progress. Of 37 patients who started the long-term study, 18 are still using the inserts-a study retention of 49%.

Publication types

  • Case Reports
  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Cellulose / administration & dosage
  • Cellulose / analogs & derivatives*
  • Cellulose / therapeutic use
  • Child
  • Delayed-Action Preparations
  • Evaluation Studies as Topic
  • Female
  • Follow-Up Studies
  • Humans
  • Keratoconjunctivitis / drug therapy*
  • Male
  • Methylcellulose / administration & dosage
  • Methylcellulose / analogs & derivatives
  • Methylcellulose / therapeutic use
  • Middle Aged
  • Sjogren's Syndrome / drug therapy
  • Stevens-Johnson Syndrome / complications
  • Xerophthalmia / drug therapy*

Substances

  • Delayed-Action Preparations
  • Cellulose
  • Methylcellulose