Haemoglobin A1: An indicator of the metabolic control of diabetic patients

Lancet. 1977 Oct 8;2(8041):734-7. doi: 10.1016/s0140-6736(77)90237-9.


The level of the minor glycosylated haemoglobins (HbA1) in ambulatory diabetic patients correlated closely with their physicians' ratings of the degree of control and their fasting plasma-glucose levels. In patients admitted to hospital for more detailed study, HbA1 correlated significantly with the mean fasting glucose, mean daily glucose, and highest daily glucose values. HbA1 measurement is a simple, rapid, and objective procedure to assess diabetic control and may serve both as a screening test for uncontrolled diabetes and as an indicator of the efficacy of various therapeutic regimens.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Blood Glucose / analysis*
  • Circadian Rhythm
  • Diabetes Mellitus / blood*
  • Diabetes Mellitus / drug therapy
  • Evaluation Studies as Topic
  • Fasting
  • Follow-Up Studies
  • Hemoglobin A / analysis*
  • Hemoglobins / analysis*
  • Humans
  • Hyperglycemia / blood
  • Hyperglycemia / prevention & control
  • Insulin / therapeutic use
  • Middle Aged


  • Blood Glucose
  • Hemoglobins
  • Insulin
  • Hemoglobin A