The morning glory syndrome associated with sphenoidal encephalocele

Ophthalmology. 1982 Dec;89(12):1368-73. doi: 10.1016/s0161-6420(82)34623-0.


A 13-year-old girl was found to have a "morning glory" optic disc anomaly associated with remnants of the primitive hyaloid vasculature, midline cleft lip and palate, agenesis of the corpus callosum, and a sphenoidal encephalocele. The association of these developmental anomalies indicates that the "morning glory" optic disc anomaly may occur as part of a more extensive syndrome of midline cranioencephalic dysraphism.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Agenesis of Corpus Callosum
  • Cerebellar Diseases / complications*
  • Child
  • Child, Preschool
  • Cleft Lip / complications*
  • Cleft Palate / complications
  • Encephalocele / complications*
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Maxilla / abnormalities*
  • Optic Disk / abnormalities*
  • Syndrome
  • Tomography, X-Ray Computed