Organization of Experimentally Induced Arterial Thrombosis in Rats: The First Six Days

Artery. 1982;11(2):156-73.

Abstract

Arterial thrombi were induced in rat aorta by a new microsurgical procedure. These thrombi, originally platelet-fibrin masses, got progressively infiltrated by various cell types. Both the importance of mononuclear cells in organization and investment and the origins of foamy cells, smooth muscle-like cells and macrophages, are discussed. Rethrombosis is regularly found at all time intervals. Thrombus volume and its position with respect to the flap are calculated.

MeSH terms

  • Animals
  • Aortic Diseases / etiology
  • Aortic Diseases / pathology*
  • Blood Platelets
  • Disease Models, Animal
  • Fibrin
  • Male
  • Rats
  • Rats, Inbred Strains
  • Thrombosis / etiology
  • Thrombosis / pathology*
  • Time Factors

Substances

  • Fibrin