Meningeal carcinomatosis with blindness

Am J Ophthalmol. 1978 Nov;86(5):661-5. doi: 10.1016/0002-9394(78)90186-1.

Abstract

A 53-year-old man had bilateral blindness secondary to meningeal carcinomatosis from pulmonary adenocarcinoma. Histopathologic examination of the visual system showed extensive infiltration of the arachnoid of the proximal optic nerves and chiasm, with minimal invasion of the optic nerves themselves. The visual pathways within the cerebral cortex were not affected.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adenocarcinoma / cerebrospinal fluid
  • Adenocarcinoma / complications*
  • Adenocarcinoma / pathology
  • Adolescent
  • Adult
  • Blindness / etiology*
  • Eye / pathology
  • Humans
  • Lung Neoplasms / complications
  • Lung Neoplasms / pathology
  • Male
  • Meningeal Neoplasms / cerebrospinal fluid
  • Meningeal Neoplasms / complications*
  • Meningeal Neoplasms / pathology
  • Middle Aged
  • Neoplasm Metastasis
  • Quadriplegia / complications
  • Schizophrenia / complications