Horner's syndrome. Criteria for oculosympathetic denervation

J Neurol Sci. 1982 Nov;56(2-3):293-8. doi: 10.1016/0022-510x(82)90150-2.


The darkness reflex of the pupil was examined by taking photographs under standard bright lighting conditions, and after 5 and 10 s of uninterrupted darkness. The study involved 40 control subjects and 12 patients with a presumed Horner's syndrome. No control subject showed a dilatation lag (compared with the other eye) of 0.5 mm or more in the first 5 s of darkness. This criterion allows exclusion of a fortuitous combination of "physiological anisocoria" and "physiological ptosis".

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Dark Adaptation
  • Horner Syndrome / diagnosis*
  • Humans
  • Iris / innervation
  • Middle Aged
  • Neural Conduction
  • Pupil / physiology*
  • Reflex, Pupillary*
  • Sympathetic Nervous System / physiopathology*