Idiopathic Pulmonary Fibrosis in Monozygotic Twins. The Importance of Genetic Predisposition

Chest. 1980 Oct;78(4):591-4. doi: 10.1378/chest.78.4.591.

Abstract

Idiopathic pulmonary fibrosis (IPF) proved by lung biopsy occurred in a pair of monozygotic twin brothers who had lived apart for many years. Histopathology of the two cases was almost identical. The purpose of this report is to substantiate the role of genetic factors in the development of IPF.

Publication types

  • Case Reports

MeSH terms

  • Diseases in Twins*
  • Environmental Pollutants / toxicity
  • Female
  • HLA Antigens / analysis
  • Humans
  • Lung / pathology
  • Male
  • Middle Aged
  • Pregnancy
  • Pulmonary Fibrosis / etiology
  • Pulmonary Fibrosis / genetics*
  • Pulmonary Fibrosis / pathology
  • Twins*
  • Twins, Monozygotic*

Substances

  • Environmental Pollutants
  • HLA Antigens