Bilateral encephaloclastic lesions in a 26 week gestation fetus: effect on neuroblast migration

Can J Neurol Sci. 1980 Aug;7(3):191-4. doi: 10.1017/s0317167100023180.


A 26 week gestation fetus with bilaterally symmetrical encephaloclastic lesions in the cerebral hemispheres is described. Information about gestation allows dating of the cerebral insult to the 3-4th fetal month. The history and morphology in this case suggest that insults occurring at or before the 3-4th fetal month interfere with normal neuroblast migration, producing a cerebral scar containing a band of neuroblasts arranged without order or lamination.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / pathology*
  • Cell Movement
  • Cerebral Cortex / embryology
  • Cerebral Cortex / pathology
  • Diseases in Twins*
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Premature, Diseases / pathology*
  • Microcephaly / pathology*
  • Neurons / pathology