Wound healing properties of naphthaquinone pigments from Alkanna tinctoria

Experientia. 1978 Nov 15;34(11):1499-501. doi: 10.1007/BF01932375.


From the roots of Alkanna tinctoria Tausch, the alkannin esters of the following acids were isolated and identified: beta,beta-dimethylacrylic acid, beta-acetoxy-isovaleric acid, isovaleric acid, and angelic acid. These esteric pigments showed excellent wound healing properties in a clinical study on 72 patients with ulcus cruris.

MeSH terms

  • Anti-Bacterial Agents
  • Humans
  • Naphthoquinones / therapeutic use*
  • Plant Extracts
  • Plants, Medicinal*
  • Salmonella / drug effects
  • Varicose Ulcer / drug therapy*
  • Wound Healing / drug effects


  • Anti-Bacterial Agents
  • Naphthoquinones
  • Plant Extracts
  • alkannin