Treatment of periodic alternating nystagmus

Ann Neurol. 1980 Dec;8(6):609-11. doi: 10.1002/ana.410080611.


Two patients with longstanding acquired periodic alternating nystagmus (PAN) were treated with baclofen, 30 mg/day. Baclofen abolished the PAN and relieved oscillopsia in both patients but was ineffective in another patient with congenital PAN.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Baclofen / therapeutic use*
  • Female
  • Humans
  • Male
  • Nystagmus, Pathologic / congenital
  • Nystagmus, Pathologic / drug therapy*


  • Baclofen