Metabolism of C-terminal pentapeptide of gastrin in the rat. Part IV. Catabolic pathways of the N-terminal BOC-14C-glycine fragment

Hepatogastroenterology. 1980 Apr;27(2):146-9.

Abstract

The catabolism of the 14C-labelled pentagastrin was investigated in rats. The following results were found: -- the labelled BOC-glycine fragment is split off the pentagastrin in the small intestine -- it is absorbed through the intestinal wall, and -- enters first the portal and then the systemic circulation.

MeSH terms

  • Animals
  • Bile
  • Carbon Radioisotopes
  • Glycine / analogs & derivatives
  • Glycine / metabolism
  • Intestinal Absorption*
  • Liver / metabolism
  • Male
  • Pentagastrin / administration & dosage
  • Pentagastrin / analogs & derivatives*
  • Pentagastrin / metabolism
  • Rats

Substances

  • Carbon Radioisotopes
  • BOC-glycine
  • rat gastrin C-terminal pentagastrin
  • Pentagastrin
  • Glycine