16 normal male adult volunteers belonging to the low socioeconomic class were investigated to study the interrelationship between vitamins E and B-complex. Vitamin E in the form of dl-alpha-tocopherylacetate at a dose of 100 mg thrice daily was administered either singly or in combination with B-complex, pyridoxine or riboflavin. Results of the study have shown that the increase in plasma tocopherol level in the group receiving vitamin E alone was significantly higher (p less than 0.01) compared to the groups receiving vitamin E along with B-complex or riboflavin.