Evoked responses in vitamin B12 deficiency

Ann Neurol. 1981 Apr;9(4):407-9. doi: 10.1002/ana.410090417.


Abnormalities of visual, brainstem auditory, and somatosensory evoked responses were demonstrated in two of seven individuals with vitamin B12 deficiency. The evoked response delays correlated directly with the degree of neurological dysfunction. Abnormalities were present in sensory systems without clinical evidence of involvement and were similar to those found in individuals with multiple sclerosis.

MeSH terms

  • Adult
  • Aged
  • Auditory Perception / physiology
  • Brain Stem / physiopathology
  • Cerebral Cortex / physiopathology
  • Electroencephalography*
  • Evoked Potentials
  • Humans
  • Median Nerve / physiopathology
  • Middle Aged
  • Peroneal Nerve / physiopathology
  • Spinal Cord / physiopathology
  • Visual Perception / physiology
  • Vitamin B 12 Deficiency / physiopathology*