Assignment to chromosome 16 of a gene necessary for the expression of human mitochondrial glutamate oxaloacetate transaminase (aspartate aminotransferase) (E.C. 2.6.1.1.)

Biochem Genet. 1980 Oct;18(9-10):947-54. doi: 10.1007/BF00500127.

Abstract

A gene necessary for the expression of human mitochondrial glutamate oxaloacetate transaminase (GOT-2) has been assigned to chromosome 16 on the basis of an immunochemical analysis of human-mouse somatic cell hybrids. Mitochondrial GOT cosegregates with adenine phosphoribosyl transferase (E.C. 2.4.2.7.).

MeSH terms

  • Adenine Phosphoribosyltransferase / genetics
  • Animals
  • Aspartate Aminotransferases / genetics*
  • Chromosome Mapping
  • Chromosomes, Human, 16-18 / ultrastructure*
  • Genes*
  • Humans
  • Hybrid Cells / ultrastructure
  • Mice
  • Mitochondria / enzymology

Substances

  • Adenine Phosphoribosyltransferase
  • Aspartate Aminotransferases