Early gastric cancer

Gastroenterology. 1981 Aug;81(2):247-56.


We found 28 cases (13%) of early gastric cancer from among 213 cases of gastric cancer resected over a 10-yr period. The incidence was higher in the second 5 yr than the first. The lesions were classified into type I (polypoid, 29%), type II (superficial, 21%). Type III (ulcerated, 32%), and mixed (18%) according to the Japanese classification. Twenty-nine percent had lymph node metastases. In only 50% of the early cases had endoscopy or radiology suggested that the lesions were malignant. Biopsy diagnosis of carcinoma was made in 20 cases preoperatively and was negative for carcinoma in 4 others. Adequate numbers of endoscopic biopsy specimens must be taken to ensure a diagnosis in early gastric cancer. Follow-ups were obtained in all early, and 70% of the advanced cancer patients. Life table survival curves revealed 5-yr survival rates for 68% for the early gastric cancer and 27% for the advanced cancer cases (p less than 0.01). None of the patients in the first group died of gastric cancer. The early gastric cancer patients had a 32% incidence of other, nongastric malignancies compared to 7.7% in the advanced cancer group. Gastric cancer is being diagnosed at an early stage and the survival rates for these patients are significantly greater than those with advanced gastric cancer.

MeSH terms

  • Actuarial Analysis
  • Adult
  • Aged
  • Biopsy
  • Female
  • Gastroscopy
  • Humans
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / diagnosis
  • Neoplasm Recurrence, Local / epidemiology
  • Neoplasm Recurrence, Local / pathology
  • Prognosis
  • Stomach Neoplasms / diagnosis
  • Stomach Neoplasms / epidemiology
  • Stomach Neoplasms / pathology*