A multivariate analysis of family data

Am J Epidemiol. 1981 Jul;114(1):149-54. doi: 10.1093/oxfordjournals.aje.a113162.


The authors describe the application of multivariate analysis to the problem of estimating intra-family correlations and testing them for statistical significance. This is illustrated by a re-analysis of survey data collected by Miall and Oldham (Clin Sci 1958;17:459-87) on the familial aggregation of blood pressure. The multivariate analysis provides collective tests of significance for parent-child and child-child correlations based on likelihood ratio theory, and maximum likelihood estimates for individual intra-family correlations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Pressure
  • Family Health*
  • Family*
  • Female
  • Humans
  • Male
  • Models, Theoretical*
  • Statistics as Topic*