The lack of toxicity of intravitreally administered triamcinolone acetonide

Am J Ophthalmol. 1981 Jun;91(6):785-8. doi: 10.1016/0002-9394(81)90013-1.


We gave one eye of each 21 rabbits an intravitreal injection of 1 mg of triamcinolone acetonide; the other eye received an injection of an equal volume of saline solution as a control. Results of slit-lamp examinations, ophthalmoscopy, intraocular pressure, electroretinography, and light electron microscopy all remained normal throughout the three-month course of the experiment, demonstrating the lack of ocular toxicity of triamcinolone acetonide in the rabbit.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Electroretinography
  • Fluorescein Angiography
  • Intraocular Pressure / drug effects
  • Ophthalmoscopy
  • Rabbits
  • Triamcinolone Acetonide / toxicity*
  • Vitreous Body / drug effects*


  • Triamcinolone Acetonide