Twenty-two cases to tuberculosis of the skull (14% of 156 cases of chronic osteomyelitis) verified by demonstration of tubercle bacilli in the discharge of cutaneous sinuses or histological examination of bone or granulation tissue are reported. Most of these patients had multiple operations elsewhere and non-healing sinuses. Three types of radiological lesion were noticed; circumscribed lytic, diffuse lytic and circumscribed sclerotic. Surgical treatment was followed by antituberculous therapy for at least 18 months. Results were excellent.