Posterior ischemic optic neuropathy

Ophthalmologica. 1981;182(1):29-41. doi: 10.1159/000309085.


3 patients (5 eyes) with posterior ischemic optic neuropathy (PION) are presented. PION is a distinct clinical entity, caused by ischemia of the posterior part of the optic nerve. These eyes presented with a visual acuity varying from normal to no light perception, optic nerve-related visual field defects, and no fundus abnormality (on ophthalmoscopy or fluorescein fundus angiography) at the onset of the disease and for about a month thereafter, but after about 5-6 weeks the optic disc developed atrophic changes. The pathogenesis, differential diagnosis and possible management of PION are discussed.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Diagnosis, Differential
  • Female
  • Humans
  • Ischemia / diagnosis*
  • Ischemia / etiology
  • Lupus Erythematosus, Systemic / complications
  • Male
  • Middle Aged
  • Optic Atrophy / complications
  • Optic Nerve / blood supply*
  • Optic Nerve Diseases / diagnosis*
  • Optic Nerve Diseases / etiology
  • Visual Acuity
  • Visual Fields